In the little Missouri town of Defiance, two small children perished in their home when it burst.
They were at home because their school had been cancelled because of the extremely cold weather.
The St. Louis Post-Dispatch said that Julian Keiser, 4, and Jamison Keiser, 6, passed away early on Friday before they could flee or be saved from their flaming house near Highway 94, just outside of St. Louis.